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Spinal Cord Injury Patient Receives Experimental Stem Cell Therapy

Wednesday, October 20, 2010

A patient with a spinal cord injury has become the first person to receive an experimental stem cell treatment that holds great promise for California spine injury lawyers.

California-based Geron Corporation announced this week that a patient who suffers from a spinal cord injury has received human embryonic stem cell therapy at an Atlanta center.  Geron Corporation is the only company in the country with approval by the Food and Drug Administration to conduct such clinical human embryonic stem cell therapies.  Geron Corporation's research into stem cell therapy is funded by private groups, which means that the company is not hindered by a recent ruling by a federal judge prohibiting the use of federal funds for human embryonic stem cell therapy research.  That ruling had severely disappointed California brain injury lawyers and researchers who had pinned much hope on such clinical trials.  But the federal ruling will not apply to the Geron trial. 

For now, this is a phase 1 trial, which means that researchers will not be looking so much at the benefits of the therapy, as much as at whether the therapy is safe to use.  The patient who is now being treated with the therapy has been admitted into Shepherd Center, which is a brain injury and spinal cord injury treatment facility in Atlanta.  The Atlanta site is one of seven potential facilities across the country where patients may be enrolled during the clinical trial. 

According to Geron, it has spent more than $130 million in developing stem cell therapies for the treatment of spinal cord injury.  Simply put, the therapy involves injecting stem cells, which have been coaxed into becoming nerve cells, directly into the injured spinal cord.  The stem cells used in the therapy are leftovers from fertility treatments.  Doctors are hoping that the stem cells will allow the nerves in the damaged spinal cord area to regenerate, ultimately to allow the patient to restore movement of injured legs and arms.

 

 

Spike in ATV-Accident Related Brain and Spinal Cord Injuries

Tuesday, October 19, 2010

A study published in the October issue of Neurosurgery shows that there has been a spike in the number of brain and spinal cord injuries resulting from ATV accidents. 

Researchers analyzed trends in ATV-related injuries in Utah between 2001 and 2005.  They found that approximately 1,500 ATV users had been injured in accidents during that period.  Approximately 50% of these persons suffered brain injuries, spinal cord injuries or both.  During each year, the researchers found there was actually a spike in the number of ATV-related head and spinal cord injuries.  Overall, between 2001 and 2005, the researchers found a 50% increase in the total number of these serious injuries.

Out of these patients, 500 suffered injuries that were serious enough to require hospitalization.  More than 50% of the patients required intensive care, and the average period of time spent in the hospital was four days.  Besides spinal cord injuries and brain injuries, the persons suffered skull injuries, facial lacerations and facial fractures.  Four patients died before they arrived at the hospital, and 15 died in the hospital.  At least 100 patients suffered a long-term impact from these injuries.  They were discharged to home health care, a rehabilitation facility or nursing home.

Most ATV-related accidents involved a vehicle rollover, which accounted for approximately 30% of injuries.  Persons below the age of 20 accounted for a high share of all ATV-related brain and spinal cord injuries.  Most injuries involved the use of a recreational ATV.  Very few injuries occurred on farms and other occupational facilities where ATVs are commonly used.

Not surprisingly to California brain and spine injury attorneys, the incidence of injury was higher for persons who were not wearing helmets while riding an ATV.  Very few cases involved the use of alcohol or drugs, although this could be due to the lack of proper recordkeeping of alcohol use as a factor in ATV-accidents.  Overall, ATV users who suffered brain and spinal cord injuries from these accidents ended up with huge medical and hospitalization expenses.

Biopharmaceutical Company Announces Data Showing Protective Effects of Multistem Therapy on Brain Injury

Tuesday, September 28, 2010

Biopharmaceutical company Athersys, Inc. has announced groundbreaking new data that shows the protective effects of Multistem therapy in the treatment of traumatic brain injury.  The company announced the publication of a study in the October issue of Experimental Neurology.  The study was conducted by researchers from Athersys, the University of Texas Medical School, Texas A&M University and other centers.

The study indicates that injections of MultiStem, the company's adult progenitor stem cell therapy product provides neurovascular protection after a person suffers from a traumatic brain injury.  The study also shows how injections of MultiStem help preserve the “blood brain barrier” and restricts the effects and extent of the injury. MultiStem is a stem cell product that uses a special class of stem cells obtained from the bone marrow and other tissue sources.  MultiStem promotes tissue repair, and aids healing without the need for immunosuppression or tissue matching. 

The new research suggests that this product can be used to great effect for multiple benefits in the case of neurological injury.  This is one of the first times that California brain injury lawyers have seen the use of a product after a traumatic brain injury, that actually acts to temper the body's responses to the injury by other organs.  The study shows that intravenous injections of MultiStem inhibit the kind of neurobehavioral damage that is often associated with traumatic brain injury.  The researchers are specifically looking at the benefits of MultiStem in treating brain injury as a result of various diseases and certain kinds of trauma.

Every year, approximately 235,000 persons in the US are hospitalized for moderate to severe traumatic brain injury.  Approximately 1.4 million people visit emergency rooms every day after suffering a brain injury.  For many of these people, the road back to recovery and rehabilitation can be extremely challenging.

Brain Injury Biomarkers Could Help Early Diagnosis

Monday, July 26, 2010

A couple of decades ago, all a doctor attending to a person with symptoms of brain injury had to work with were the symptoms as described by the patient.  Then, scientists discovered that when a person suffers a loss of oxygen in the blood, a chemical called troponin is released in the blood.  Now, a quick blood test confirms the presence of this chemical.  If a new study is successful, physicians will soon be able to use such biomarkers to detect that a person has suffered a brain injury.

Early diagnosis of brain injury and treatment as quickly as possible are the key factors in limiting the damage caused by these catastrophic injuries.  Unfortunately, very often, doctors fail to diagnose brain injury, like when a person continues to remain conscious after an injury.  Just because a person has remained conscious does not mean that there is no injury.  Currently, doctors are also not in a position to be able to correctly diagnose immediately whether the person has suffered a brain injury, or is having a stroke or some other condition.  This frequently leads to a wrong diagnosis, delayed treatment and ultimately, a lifetime of severe mobility for the patient.

That unfortunate situation could soon change, however.  The US Defense Department is funding a study of brain injury biomarkers in more than 1,000 patients.  The study will be conducted across 20 hospitals both inside the US and abroad.  It is believed to be the first study of its kind anywhere in the world, and California brain injury lawyers believe could revolutionize the way physicians diagnose brain injuries.  The US military is pinning its hopes on the locating of biomarkers to diagnose brain injury.  If that happens, a simple blood test and a physician would be able to detect the presence of a brain injury, and could begin treatment immediately. 

Patients with Brain Injury Eight Times More Likely to Suffer from Serious Depression

Thursday, June 10, 2010

You don't need a study to learn certain facts. But solid research can confirm the kind of long-term health impacts that brain injury patients suffer. A new study shows that patients who suffer a massive brain injury have a risk of suffering depression that is up to eight times higher than for persons without a brain injury.

The study was conducted by a team at the University of Washington School of Medicine in Seattle. The team studied a total of 559 patients who had suffered a traumatic brain injury. Of these patients, approximately 53% had suffered major depression after the injury.

The risks of suffering severe depression were not the same for all brain injury patients. For instance, patients who already suffered from depression at the time of their injury or just before the injury, were more likely to fall into a major depression soon after the head injury. Younger patients were also at a higher risk for depression after brain injury. Patients, who had a dependence on alcohol and substance use, were also more likely to suffer major depressive disorders after brain injury. Brain injury patients, who suffered from major depression, were also at a high risk for anxiety disorders.

The study also threw some light on the lack of proper care for brain injury patients who also suffered from depression. The study found that just about 44% of the brain injured patients who suffered from depression received any treatment for their depression. This only exacerbated their symptoms, and negatively impacted their quality of life.

Many brain injured patients can expect a diminished quality of life. The lucky ones may be able to perform routine daily tasks without much help, walk, and even go back to a job. The unfortunate ones however, find it difficult to perform even routine daily activities, and may be unable to play sports, or go back to work. In a situation like this, it's not hard for California brain injury lawyers to see how depression can set in.

Man Sues Cheyenne Wyoming Police for Brain Injury

Thursday, April 22, 2010

A Cheyenne, Wyoming, resident has filed a federal civil suit against the city, claiming that city police caused a man lasting brain damage in a 2007 arrest that violated his constitutional rights.

Iva McClinton filed the complaint on behalf of her son, Daris R. Peters. The suit alleges that three Cheyenne officers held Peters face down on the ground while handcuffing him during the arrest on April 16, 2007. This cut off the flow of oxygen to his brain, causing him to stop breathing. Court documents said that this lack of airflow caused brain damage as a result of cardiac arrest and anoxic encephalopathy.

In addition to naming the city, the suit names officers Geffery Mims, Kent Davis and Stephanie Nation, as well as the police department as a whole.

Court documents filed on behalf of the officers said they were called to the scene because of Davis' behavior as he was walking near an apartment in the area. The documents did not specify the nature of the behavior mentioned.

Reports indicate that Davis was tasered at least five times during the arrest, in addition to the alleged suffocation from being held down.

“After handcuffing (Peters’) hands behind his back, he was physically held in a prone position by all three officers, with at least one officer placing his knee on (Peters’) back,” the complaint said. “Even though (Peters) began gasping for air and had difficulty breathing, the officers did not turn (Peters) over and put him in a position where he could breathe properly.”

The suit is seeking $840,000 in medical costs, along with court expenses and possible punitive damages.

The police department declined all comment in the matter, saying they did not have any information or know when it would be appropriate to discuss their strategy in the case. The department has retained counsel for the officers’ defense. Casper attorney Patrick Murphy has been assigned to represent both the officers and the department as a whole in the matter.

First NFL Brain Injury Group Meeting in Florida

Saturday, February 06, 2010

The relationship between professional football and brain injury has been heavily in the media spotlight over the past few months. The issue has even gone to Congress. This week, the Mackey-White Traumatic Brain Injury Committee held its first meeting in Palm Beach, Florida. The committee consists of professional athletes, current and past NFL players, doctors and scientists. The committee has been formed as a forum for discussion of brain injuries in professional football, the latest research linking these injuries to football, as well as safety recommendations to prevent injuries. The committee is named after athletes John Mackey who suffers from Alzheimer’s disease and Reggie White, who died at the age of 43 after his retirement from professional football.

Congressional hearings into the link between professional football and dementia and other signs of brain injury were conducted earlier this month. It was a follow up to a compete hearing conducted in October last year in Washington.  During that hearing, the NFL had received severe criticism for the manner in which it has handled the issue of brain injuries in football players.  The league has since agreed to several changes in the rules to minimize the risk of such injuries.

For California brain injury lawyers, getting the NFL to even admit that there is a high risk of brain injuries with the kind of continuous blows to the head that a professional football player receives, has been no easy task. The NFL’s Dr. Ira Casson testified before the hearing earlier this month - and continues to insist -  that there wasn’t enough evidence to determine if repeated head blows could cause long-term brain damage.  However in December last year, an NFL spokesman made a startling admission - that medical research had proved that repeated concussions can cause long-term problems.  It should hopefully, signify the beginning of better safety measures to prevent these debilitating injuries.

Study Says Concussions are Brain Injuries Too

Thursday, December 24, 2009

A Canadian group of researchers says that a concussion is not just a minor head injury, but a brain injury that parents must take more seriously.

Researchers at the School of Rehabilitation Science at McMaster University in Hamilton, Ontario say that although the term “concussion” is used loosely to signify any kind of minor injury or head bump, these injuries are more serious than most of us know. The researchers reviewed 434 children with brain injuries. Of these kids, 32 percent had suffered a concussion.  The researchers found that:

  • Children who had suffered a concussion were required to stay in the hospital for a lesser amount of time.
  • They also spent fewer days off school.
  • Not only that, they also returned to school soon after being discharged from the hospital without a lengthy recuperation period.

According to Dr. Carol DeMatteo, who is an associate clinical professor at the School of Rehabilitation Science, children who return to school or begin to play sports soon after a concussion are at a higher risk of suffering another head injury. In fact, these children are twice as likely to suffer a second head injury within a period of one year. This second injury can actually end in serious or permanent brain injury.

Concussions are typically not taken seriously. Once the bump disappears and the pain is gone, parents assume that their children are fine and don’t need additional treatment. However, Dr. DeMatteo warns that children who suffer a concussion must be monitored, and kept under observation. This is especially so if the CT scan shows brain damage, or if the child has lost consciousness for a long period of time. In such cases, the child may have suffered a more severe brain injury which is not visible from the outside. Externally, the child may be able to perform normal activities without any signs of damage, but such injuries could turn very serious or fatal quickly. 

As California brain injury lawyers, we would also advise schools, teachers and coaches to monitor such injuries in students. Children who have suffered concussions must not be allowed to play rough sports before confirming that there is no underlying brain damage.

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